| 008 |
|
200901n^^^^^^^^xx^^^^^^s^^^^^^^^^^^eng^d |
| 245 |
00 |
|a Resting State Functional Connectivity of the Periaqueductal Gray Area (PAG) in Association to Threat Bias in Anxiety Disorders |h [electronic resource]. |
| 520 |
3 |
|a The periaqueductal grey area (PAG) is highly involved in processing pain and fear. This study evaluated the resting state functional connectivity (rsFC) of the periaqueductal gray area (PAG) in healthy controls (HC) and patients with anxiety related disorders (PAD). Functional magnetic resonance imaging (fMRI) and behavioral data were obtained from the Nathan Kline Institute (NKI) - Rockland Sample. Participants completed a 5-minute resting fMRI scan and a dot-probe task outside the scanner. The dot-probe task consisted of two emotional faces (happy, threatening, or neutral) appearing on a screen, one of which would be replaced by a dot that required a button press. Reaction time was computed as the difference in reaction time (RT) between the dot replacing the neutral faces and the threatening faces (i.e., RT in neutral – RT in threat). Positive threat bias reflects faster response for threatening faces that might indicate severe pain and anxiety. The rsFC of the whole brain connectivity showed no differences of PAG rsFC between both HC and PAD. Regression analysis showed a significant and negative correlation between the left PAG-putamen rsFC and Threat Bias in PAD but not in HC, suggesting a disruptive coupling between PAG and putamen in severe pain in anxiety disorders. The PAG-putamen connectivity might serve as an important neural indicator of anxiety disorders.
|
| 533 |
|
|a Electronic reproduction. |c SUNY Oswego Institutional Repository, |d 2020. |f (Oswego Digital Library) |n Mode of access: World Wide Web. |n System requirements: Internet connectivity; Web browser software. |
| 535 |
1 |
|a SUNY Oswego Institution. |
| 541 |
|
|a Collected for SUNY Oswego Institutional Repository by the online self-submittal tool. Submitted by Kelsey Roberts. |
| 720 |
|
|a Kelsey Roberts |u SUNY Oswego -- Liberal arts -- Psychology. |
| 830 |
0 |
|a Oswego Digital Library. |
| 830 |
0 |
|a SUNY Oswego Scholarly and Creative Works. |
| 830 |
0 |
|a Summer 2020 Scholarly and Creative Activities Symposium. |
| 852 |
|
|a OswegoDL |c SUNY Oswego Scholarly and Creative Works |
| 856 |
40 |
|u https://digitallibrary.oswego.edu/AA00000235/00001 |y Electronic Resource |
| 992 |
04 |
|a https:/digitallibrary.oswego.edu/content/AA/00/00/02/35/00001/CN_Lab_RISE_Poster_2020_Final_Draftthm.jpg |
| 997 |
|
|a SUNY Oswego Scholarly and Creative Works |